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1.
Lactate dehydrogenase isoenzyme patterns in human foetal tissues during development.
Subhash, M N; Shankar, S K; Rama, B S.
Indian J Physiol Pharmacol ; 1986 Oct-Dec; 30(4): 271-9
Article in English | IMSEAR | ID: sea-107207

ABSTRACT

The changes in lactate dehydrogenase isoenzyme fractions in various tissues from human foetuses were studied at different stages of development. The isoenzyme pattern changes with the gestation period. The adult pattern is attained at birth in heart, liver, muscle and kidney. Brain shows predominance of cathodic fractions even at birth, but becomes aerobic after 6-12 months. LDH1/LDH5 ratio shows a similar trend. It appears that the adult pattern of LDH isoenzymes consists of predominantly either the faster (aerobic tissues) or slower (anaerobic tissue moving isoenzymes resulting from a gradual shift during foetal and neonatal life.


Subject(s)
Embryonic and Fetal Development , Fetal Heart/enzymology , Fetus/enzymology , Humans , Isoenzymes , L-Lactate Dehydrogenase/metabolism
2.
Homocystinuria--a cause for stroke in young.
Taly, A B; Nagaraja, D; Subhash, M N.
Article in English | IMSEAR | ID: sea-90088

Subject(s)
Adult , Cerebrovascular Disorders/etiology , Homocystinuria/complications , Humans , Male , Pyridoxine/therapeutic use , Recurrence , Vertebrobasilar Insufficiency/etiology
3.
Homovanillic acid & 5-hydroxy indole acetic acid in the CSF in rheumatic chorea.
Nagaraja, D; Srinivasa, R; Subhash, M N; Rao, B S.
Article in English | IMSEAR | ID: sea-18767

Subject(s)
Adolescent , Adult , Child , Female , Humans , Male
4.
Biochemical screening and mental retardation.
Sridhara Rama Rao, B S; Jayasimha, N; Subhash, M N.
Indian J Pediatr ; 1982 May-Jun; 49(398): 361-5
Article in English | IMSEAR | ID: sea-81805

Subject(s)
Body Fluids/analysis , Humans , India , Mass Screening , Intellectual Disability/epidemiology , Metabolism, Inborn Errors/epidemiology
5.
Erythrocyte lithium efflux in mania.
Sampath, G; Sridhara Rama Rao, B S; Subhash, M N; Channabasavanna, S M.
Article in English | IMSEAR | ID: sea-20270

Subject(s)
Affective Disorders, Psychotic/metabolism , Bipolar Disorder/drug therapy , Dose-Response Relationship, Drug , Erythrocyte Membrane/metabolism , Humans , Lithium/metabolism
6.
Body weight--dose relationship of lithium carbonate in manics.
Sampath, G; Channabasavanna, S M; Sridhara Rama Rao, B S; Subhash, M N.
Article in English | IMSEAR | ID: sea-21467

Subject(s)
Adolescent , Adult , Aged , Bipolar Disorder/blood , Body Weight/drug effects , Dose-Response Relationship, Drug , Female , Humans , Lithium/blood , Lithium Carbonate , Male , Middle Aged
7.
Lithium excretion and therapeutic response in mania.
Sampath, G; Channabasavanna, S M; Rao, B S; Subhash, M N.
Article in English | IMSEAR | ID: sea-22295

Subject(s)
Adult , Affective Disorders, Psychotic/drug therapy , Bipolar Disorder/drug therapy , Female , Humans , Lithium/therapeutic use , Male , Middle Aged
8.
Biochemical screening in mental retardation.
Rao, B S; Jayasimha, N; Subhash, M N.
Indian J Pediatr ; 1981 Mar-Apr; 48(391): 229-34
Article in English | IMSEAR | ID: sea-81178

Subject(s)
Humans , India , Infant, Newborn , Mass Screening , Intellectual Disability/diagnosis , Metabolism, Inborn Errors/diagnosis
9.
Monitoring of serum lithium levels in manic depressive psychosis.
Subhash, M N; Narayanan, H S; Rao, B S; Channabasavanna, S M.
Article in English | IMSEAR | ID: sea-19381

Subject(s)
Adult , Bipolar Disorder/blood , Female , Follow-Up Studies , Humans , Lithium/blood , Male
10.
Metabolic anomalies detected during a systematic biochemical screening of mentally retarded cases.
Rao, B S; Subhash, M N; Narayanan, H S.
Article in English | IMSEAR | ID: sea-26120

Subject(s)
Adolescent , Amino Acid Metabolism, Inborn Errors/epidemiology , Child , Child, Preschool , Female , Humans , India , Infant , Male , Intellectual Disability/etiology , Phenylketonurias/epidemiology
11.
Hydroxyprolinemia: a case report.
Rama Rao, B S; Subhash, M N; Narayanan, H S.
Indian Pediatr ; 1974 Dec; 11(12): 829-30
Article in English | IMSEAR | ID: sea-6863

Subject(s)
Amino Acid Metabolism, Inborn Errors , Child , Humans , Hydroxyproline/blood , Male
12.
Histidinemia. Report of a case.
Rao, S R; Subhash, M N; Narayanan, H S.
Indian J Pediatr ; 1974 Sep; 41(320): 312-3
Article in English | IMSEAR | ID: sea-82536

Subject(s)
Amino Acid Metabolism, Inborn Errors , Child , Histidine/blood , Humans , Male
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